Autoimmune Polyendocrinopathies

Autoimmune diseases affecting multiple endocrine organs. Type I is characterized by childhood onset and chronic mucocutaneous candidiasis (CANDIDIASIS, CHRONIC MUCOCUTANEOUS), while type II exhibits any combination of adrenal insufficiency (ADDISON'S DISEASE), lymphocytic thyroiditis (THYROIDITIS, AUTOIMMUNE;), HYPOPARATHYROIDISM; and gonadal failure. In both types organ-specific ANTIBODIES against a variety of ENDOCRINE GLANDS have been detected. The type II syndrome differs from type I in that it is associated with HLA-A1 and B8 haplotypes, onset is usually in adulthood, and candidiasis is not present.

Also Known As:

Schmidt Syndrome; Schmidt's Syndrome; Autoimmune Polyendocrinopathy; Polyendocrinopathies, Autoimmune; AIRE Deficiency; APECED; APS Type 1; Autoimmune Polyendocrine Syndrome, Type 2; Autoimmune Polyendocrine Syndrome, Type II; Autoimmune Polyendocrinopathy Syndrome Type 1; Autoimmune Polyendocrinopathy with Candidiasis and Ectodermal Dystrophy; Autoimmune Polyendocrinopathy- Candidiasis- Ectodermal Dystrophy; Autoimmune Polyglandular Syndrome Type I; Autoimmune Polyglandular Syndrome Type II; Autoimmune Polyglandular Syndrome Type III; Autoimmune Polyglandular Syndrome, Type 1; Autoimmune Polyglandular Syndrome, Type 3; Autoimmune Polyglandular Syndrome, Type I; Autoimmune Syndrome Type III, Polyglandular; Diabetes Mellitus, Addison Disease, Myxedema; Diabetes Mellitus, Addison's Disease, Myxedema; Multiple Endocrine Deficiency Syndrome, Type 2; Polyendocrine Autoimmune Syndrome, Type II; Polyendocrinopathy- Candidiasis- Ectodermal- Dystrophy, Autoimmune; Polyglandular Autoimmune Syndrome, Type 1; Polyglandular Autoimmune Syndrome, Type 2; Polyglandular Autoimmune Syndrome, Type 3; Polyglandular Autoimmune Syndrome, Type I; Polyglandular Deficiency Syndrome, Type 2; Polyglandular Type III Autoimmune Syndrome; AIRE Deficiencies; Autoimmune Polyendocrinopathy Candidiasis Ectodermal Dystrophy; Deficiency, AIRE; Polyendocrinopathy Candidiasis Ectodermal Dystrophy, Autoimmune; Polyendocrinopathy, Autoimmune; Polyendocrinopathy- Candidiasis- Ectodermal Dystrophy, Autoimmune; Syndrome, Schmidt; Syndrome, Schmidt's; Autoimmune Polyendocrinopathy- Candidiasis- Ectodermal- Dystrophy; Autoimmune Syndrome Type I, Polyglandular; Autoimmune Syndrome Type II, Polyglandular; Polyglandular Type I Autoimmune Syndrome; Polyglandular Type II Autoimmune Syndrome

Endocrine System Diseases: 996
- Autoimmune Polyendocrinopathies: 351
Immune System Diseases: 4430
- Autoimmune Diseases: 35458
  - Autoimmune Polyendocrinopathies: 351

Taina Rüppell Selected Research

Taina Rüppell Research Topics

Disease

Drug/Important Bio-Agent (IBA)